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pharmacogenomics

Pharmacogenomics

1.Pharmacogenomics is the study of the role of the genome in drug response. Its name reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of an individual affects his/her response to drugs. 

2.pros
  • Improve drug safety, and reduce ADRs;
  • Tailor treatments to meet patients' unique genetic pre-disposition, identifying optimal dosing;
  • Improve drug discovery targeted to human disease; and
  • Improve proof of principle for efficacy trials
3.genome-wide technology on pharmacogenomics of mental illnesses including schizophrenia (SCZ), autism spectrum disorders (ASD), attention deficit hyperactivity disorder (ADHD), and obsessive compulsive disorder (OCD).

4.The effectiveness and toxicities of medications used in secondary stroke prophylaxis, dementia, seizure disorders, multiple sclerosis (MS), and Parkinson disease (PD) are all influenced by genetic polymorphisms.

5.pharmacogenomic  used to study neurodegenerative disorders

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