Neuropsypharmacology

Major new medicinal drugs to treat depression :  1.Onion ( Allium cepa) -Quercetin glycosides  -MAO inhibitor 2.Green tea -polyphenols, catechins -regulate HPA axis activity 3.Clove -Kaempferol -MAO inhibitor 4.Lemon - apigenin ,essential oil, flavanoid - elevate platelet Adenyl cylase activity ,Activate serotonergic and dopanergic activity ,   5.Coriander  -  querectin -MAO inhibitor Other: 6. Crocus sativus .L 7.Zingiber officinale Rosco - phenolic constituents shogaol  -The alcoholic extract of the ginger at a dose of 300 mg/kg is found to be effective nearly similar to standard drug fluoxetine in FST. 8. Glycirrhiza glabra -flavonoids such as  liquiritin and isoliquiritin (at doses of 10, 20 and 40 mg/kg) in licorice have been reported to exhibit an antidepres- sant activity in mice models 9 .Lavendula officinalis ( lavender) - These phytochemicals are estimated  to be responsible for the sedative activity of the plant via γ-aminobutiric acid...

Major points in pharma times Oct 19 1.Stephan and James Huang to develop vaccines for cancer. It works by mRNA encoding for protein that neutralize cancer cells. 2. Lonsurf(triflurodine) to treat gastric cancer. ROCHE's Tensertiq(atezolizumab) to treat metastatic lung cancer. 3.Novartis's Ofatumumam more effective than Sanofi's Aufagio to treat multiple sclerosis. 4UK uses biosimilar medicines , saves £200 5.Statins to be prescribed by pharmacist . Main points in pharmacy times: Oct19 Drug therapy of choice to treat inflammation -biological DMARDS (tissue necrotic factor blocker)::subcutaneous olimumab -convention DMARDS :methotrexate -Tcell costimulation modulator -Non biological DMARDs  * Disease-modifying antirheumatic drugs ( DMARDs ) are a group of medications commonly used in people with rheumatoid arthritis. Some of these drugs are also used in treating other conditions such as ankylosing spondylitis, psoriatic arthritis, and systemic lupus erythematosus.